Iron saved soft tissue in Dinosaur fossils?
The iron nanoparticles, however, may be doing more than just preserving
tissues.
Despite what happens in the science fiction world of “Jurassic Park”,
no dinosaur DNA has yet been found. The reason for this is that DNA is thought
to have a half-life of 521 years, so what could be left after the 65 million
years or so that stand between humanity and dinosaurs? But could the iron-based preservation process might
allow DNA to bypass its typical half-life and last a lot longer.
To find that out, Dr Schweitzer and the team used an iron-removal compound to delicately
pull iron away from the dinosaur tissues without damaging them. They then added
four different stains that react only with either DNA itself, or with proteins
closely associated with it in organisms other than microbes. Remarkably, in all
cases, these specific stains lit up inside the ancient cells in the tissue
samples. This hints that something chemically very similar to DNA can remain in
a fossil and might yet be hidden precisely where it had resided during life.
As to whether any DNA strands can ever be read remains to be determined
because of the complex knots that they have been tied into by the iron. But Dr
Schweitzer and Dr Goodwin plan to try. Many things other than iron tie proteins
into knots. One is sugar which, when exposed to tissues in high enough
concentrations, can also cause abnormal bonds to form. This process damages
tissues in diabetics. Some doctors suspect the process might be reversible by
using drugs, like N-phenacylthiazolium bromide, that selectively cleave
abnormal bonds while leaving normal ones alone. With this in mind, the
researchers are considering trying some of these drugs on their dinosaur
proteins to see if they can untangle them.
In the end, such tactics will not be quite as poetic as Hollywood’s
notion of collecting dinosaur DNA from bloodsucking mosquitoes preserved in
tree sap. But if it results in sequencing even part of the genes of a T. rex to
determine more about these and other prehistoric animals, then no one is going
to mind.
Source: The Economist
Source: The Economist